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 Profhilo vs. Profhilo Structura: Understanding the Differences 

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April 28, 2025
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In the world of aesthetics, injectable treatments have come a long way, offering options that can significantly improve skin texture, tone, and overall appearance. Two popular treatments in the hyaluronic acid (HA) injectables category are Profhilo and Profhilo Structura.  While both are designed to enhance the skin’s elasticity and hydration, they differ in formulation and specific benefits. Here’s a closer look at each treatment, and how they compare. 

What is Profhilo? 

Profhilo is a revolutionary treatment that uses a unique formulation of hyaluronic acid to improve skin quality. It’s a bio-remodeling injectable that works on skin laxity, hydration, and texture by stimulating collagen and elastin production. Unlike traditional fillers, Profhilo doesn’t add volume to the face. Instead, it spreads evenly across the skin to rejuvenate, hydrate, and revitalize the skin from within. 

Profhilo is known for its: 

– Skin hydration- The high concentration of hyaluronic acid attracts moisture, making the skin plumper and more hydrated. 

– Collagen stimulation- It encourages the production of collagen and elastin, improving skin’s firmness and elasticity. 

– Natural results-  Since it doesn’t change facial volume, the results are more subtle, with improved skin quality over time. 

Typically, Profhilo is used for facial areas that show signs of aging, like the cheeks, under the eyes, neck, and hands. The treatment involves two sessions, spaced about 4 weeks apart, with noticeable improvements in skin texture, tightness, and overall radiance. 

What is Profhilo Structura? 

Profhilo Structura is an advanced version of the original Profhilo treatment. While it contains the same key ingredient—hyaluronic acid—Profhilo Structura is designed to offer more targeted skin remodeling and firming. The “Structura” version is aimed at patients who want to address deeper skin concerns such as loss of volume, sagging, and significant skin laxity, especially in the mid-face and jawline areas. 

Profhilo Structura offers: 

-Enhanced skin remodeling- The formulation contains a more cross-linked version of hyaluronic acid, which provides a denser and more structural effect on the skin. This is particularly effective for areas with more significant sagging or aging. 

– Volume restoration-  Unlike standard Profhilo, which is more focused on hydration and skin health, Structura has a more lifting effect, helping to restore a more youthful, lifted appearance to areas that have lost volume. 

– Targeted firming- Profhilo Structura targets specific areas like the lower face, jawline, and cheeks, where sagging and loss of contour are more pronounced. 

The treatment involves a series of injections that are slightly deeper than the original Profhilo to provide both hydration and volumizing effects, improving overall facial structure. Two sessions are generally required, spaced a month apart, and results can be seen in 4-6 weeks after treatment. 

Key Differences Between Profhilo and Profhilo Structura** 

1. Formulation 

   – Profhilo- A standard hyaluronic acid-based treatment designed to hydrate and improve skin texture. 

   – Profhilo Structura Uses a more advanced formulation of cross-linked hyaluronic acid to offer structural and volumizing benefits, particularly in areas with greater laxity. 

2. Treatment Goals 

   – Profhilo- Focuses on improving skin hydration, elasticity, and general skin quality. 

   – Profhilo Structura-  Aims to restore volume, lift sagging skin, and firm areas that have experienced significant aging or skin laxity. 

3. Areas of Use 

   – Profhilo- Can be used on a wider range of areas including the face, neck, hands, and décolletage. 

   – Profhilo Structura- Primarily targeted at the lower face (jawline, cheeks) and other areas showing noticeable sagging or volume loss. 

4. Depth of Injection 

   – Profhilo- Shallow injections into the dermis to promote hydration and skin quality. 

   – Profhilo Structura- Slightly deeper injections for more intensive remodeling and firming effects. 

5. Results 

   – Profhilo- Results are more subtle, providing a radiant and hydrated appearance with improved skin texture. 

   – Profhilo Structura- Results are more pronounced, offering lifting and tightening, as well as more volume restoration. 

Which One Should You Choose? 

The choice between Profhilo and Profhilo Structura depends on your skin’s needs and goals: 

– If you’re primarily looking to hydrate your skin and improve overall texture with a more natural look, Profhilo may be the right choice for you. 

– If you’re dealing with deeper skin laxity, volume loss, or sagging, particularly in the jawline and cheek area, then Profhilo Structuramay be more appropriate, as it provides more lifting and structural support. 

Final Thoughts 

Both Profhilo and Profhilo Structura offer incredible benefits for skin rejuvenation, but the key difference lies in the depth and focus of their treatments. While Profhilo is excellent for hydration and improving skin quality, Profhilo Structura goes a step further by targeting skin sagging and offering more volumizing effects. Whatever your skin concerns may be, consulting with a qualified aesthetic practitioner can help you determine which treatment will give you the best results for your unique needs. 

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